MTF,the worlds larges accredited tissue bank, has just introducedRENUVA! This is an Allograft Adipose Matrix or in plain English, adipose cellular material from the highest quality donors. The "remnants" of the fat cells (processed to keep the fat stimulation properties) have no imunogenic activity. Thus no skin test is necessary. No anesthesia is necessary! This could replace fat grafts in small volumes and can be used to correct minor "dents". Of course this is being used in cosmetic procedures to rplace certain fillers. Cheeks and hands are two areas that have caught the attention of some of the early adopters of this new Biostimulator.
Cheek Volume Restoration
In essence the material comes in a syringe and it is prepared by mixing or rehydrating it with saline. It is then ready for injection! The material tricks the body into making fat where it has been injected. Most studies demonstrate a 40% volume retentin long term in areas treated with RENUVA. AS larger volumes become available surgeons and dermatologists will address "Larger targets" such as buttocks or even breasts!
While Autologous Fat grafts will not be replaced by these Allograft Adipose Matrixes, they will add one more tool into our cosmetic and reconstructive group of options. The growth factors contained in the Renuva has even been shown to help heal certain types of wounds and soften longstanding scars much like those autologous fat grafts/ Call the office at 2390348-7362 to see if this could be benficial to your goals.
There is a new combination of Non-Surgical neck lift that combines Thermi (Radiofrequency heating) of the skin with micro suctioning of the fat under the skin and below the jaw line. The "tightening" usually takes place over a year or so. To speed up the process with an immediate result, we have added the use of barbed sutures that are placed through the same punctures used for the Thermi and micro-liposuction. The procedure is done under local anesthesia and takes approximately 45 minutes from beginning to end. Downtime can be as little as 48 hours and discomfort is minimal. Here is an interview with the patient that has undergone this procedure.
Androgenic alopecia (hair loss sensitive to Testosterone) is the most common type of hair loss in both men and women. Follicles are “ miniaturized” and hair gets thinner before it falls out. All the following treatments work better on recent hair loss and in areas that still have some active but miniaturized follicles. If these methods are to work there will be results in 6-9 months usually at the most 12 months. Occasionally the PRP injections will work even in cases of autoimmune types of alopecia.
Topical treatments for alopecia have been around for over 20 years in the form of minoxidil (Rogaine). This was originally a blood pressure medication and has been recently found to probably increase the circulation to the hair follicles. This is in contrast with the oral agents such as finasteride (Propecia) that are 5-alpha reductase inhibitors (they block the conversion of testosterone to dihydrotestosterone). As you can imagine the side effects of these agents orally can be significant and they can include loss of libido difficulty with ejaculation and so forth. Although topical compounds from these have been made the original minoxidil Rogaine formulations were now well received by the public probably because of the high percentage of propylene glycol used as a delivery agent. A much better formulation 82M was developed which included minoxidil at 7% plus tretinoin (which helps the absorption of the rest of the medications), a topical steroid most commonly betamethasone and an organic 5 alpha reductase inhibitor Oleanic Acid.
We have this available as a topical agent by itself or as a shampoo with or without some of the other delivery system such as the micro-needling and micro-needling with PRP. In addition to this will also offer oral agents that are purely building blocks for the hair follicles. Essentially vitamins that the body continues to stimulate and maintained good hair growth.
Now a little bit about what happens with the PRP and with some of the other growth factor stimulation of the hair follicles. The hair follicles have been found to be stimulated by several things from low level laser treatments that are springing up all over the place to increase the blood supply through minoxidil topically or by blocking the action of testosterone on the health follicles through some of the blocking agents (as a medication or an organic compound). Most recently the stimulation of the follicles directly by platelet derived growth factors such as VEGF also known as vascular endolthelial growth factor and several others found in the platelets have adirect stimulatory effect on the numbers of hair follicles that are active and the thickness of the hair they produce!.
Other Growth factors derived from fat cells have also been used with Microneddling and have been shown to have a stimulatory effect on the hair follicles. These are producta available "Off the shelf" without requiring a blood draw ad platelet gel preparation. These substances combined with mechanical stimulaion caused by the micronnedling itself can lead to a "perfect storm" type of effect.
Option #1 oral supplements to stimulate
Option #2 oral supplements plus a topical agent such as 82M which come by a high percentage minoxidil with tretinoin and betamethasone along with oleanic acid (to block testosterone from becoming dihydrotestosterone). The Shampoo 82 S has pure organic agents
Option #3 addition of micro-needling using 82M or another off-the-shelf hair growth stimulation with the growth factors derived from fat cells.
Option #4 is the most aggressive which includes micro-needling with PRP and any of the additional oral or topical agents post procedure. Both option #3 and #4 are spaced about 4-6 weeks apart and include a series of 3 treatments for maximum stimulation. Expect significant improvement proximal 6 weeks after the second treatment. Yearly treatments are recommended for maintenance of maximal stimulation of growth. Not all treatments will work on everyone and sometimes we have to try different ones to maximize hair growth.
The more we learn about our body's ability to stimulate healing and regenerate itself, the more we find innovative ways to restore the failing parts of her body. Platelet rich plasma also known as PRP is a highly concentrated suspension of our own bodies healing triggering bodies known as platelets. They contain a myriad of hormones or 'factors' that begin and stimulate the process of 'wound healing' and repair in many different ways. For hair stimulation the epithelial growth factors are the most valuable. The stimulate the hair follicles in 2 ways. First is to increase the circulation to the follicles at critical moments in the development of the hair thus making the hair thicker (up to 40%) and 'waking' up some of the hair follicles that were in the resting or dormant phase (>20%).
The Platelet Rich Plasma (PRP) is made by drawing your blood and centrifuging or spinning this blood to concentrate the platelets and remove the red blood cells. This allows only the stimulating platelets without the remaining parts of the blood which can have an irritating the effect.
So what is the process to get the platelet gel to the targeted hair follicles. One way to admisnister it is to inject the scalp or any other area in which you want to stimulate hair growth at a level where these hair follicles are (between 2 and 3 mm deep) or we can use a micro-needling device which essentially pokes tiny needle holes to the same level. The needle holes themselves will stimulate a similar response from the hair follicles and this is only augmented by the application of the platelet gel that trickle down into these holes while they are still open. This is usually combined with an injection of the remainder of the platelet gel deep to the hair follicles after the micro-needling.Thus the termMicroneedling with PRP
Microneedling with PRP
This process is not only for male pattern baldness but also useful for the thinning hair experienced by more and more women these days. Recent studies have shown this to be highly effective in treating alopecia areata which appears to have an autoimmune component. The process is repeated an average of 3 times about 6 weeks apart. We start seeing significant improvement at the 3-4 month stage after the initial treatment. And it is recommended that once a year another session of micro-needling plus PRP is used as a booster to keep the hair growth:. We often combined this with topical applications which work in many different ways. The most common affect is to block the testosterone effect on the hair follicle itself and other parts of these formula help keep the scalp cleaned by turning over the new cells and clearing the path for the hair follicle growth. Please call La-Piel Spa at 239-352-5554 for your evaluation and to get you started on stimulation of your own lush beautiful hair.
Originally micro-needling was performed with needles of varying lengths on a roller. These are replaced by battery-operated hand-held "micro-needling" pens that were based on tattoo machines. The purpose of the needle punctures was to stimulate wound healing and trigger collagen and elastin production as well as skin remodeling. The total result was from the needle puncture alone!
Soon afterwards the use of post micro-needling topical agents were introduced. Research showed that for 20 minutes after the procedure 'channels' or microscopic holes were open to allow delivery of products and substances to the deep ( active) layers of the skin called the deep dermis. These areas happened to be where a lot of the pigment is produced as well as the thicker collagen and blood vessels. At first only antioxidant vitamins such as topical vitamin A and vitamin C were used. Later bleaching agents ( hydroquinones and Kojic acid) and hydrating agents such as Hyaluronic Acids were added to the list a post-treatment topical agents.
As part of the new wave of investigations in the field of regenerative medicine we have found that the single most active post procedure topical is autologous platelet rich plasma or PRP. This utilizes a specific part of your on blood to "supercharge" the healing process. The platelets contain proteins that act as messages to get the body to deliver "repair materials" to the area your treating. The combination of micro-needling plus PRP has been found effective in repairing sun damaged skin, acne scarring, surgical scars, burn scars, hyper and hypo-pigmentation, as well as crinkly skin and fine lines. Recently studies of shown this combination to be particularly helpful and stimulating hair growth in certain types and thinning hair conditions. Approximately 2 ounces of your blood was drawn and processed while a topical anesthetic cream is administered to the area to be treated. This is then sprayed during the procedure and immediately after the procedure. Any leftover PRP can be injected just underneath the scan to further stimulate the healing process.
Microneedling with PRP
Micro-needling is performed and a series of 3-5 treatments 2-3 weeks apart and there is no real downtime. A flushed appearance and a recommendation to avoid the sign the next few days after the procedure of the only signs a give had something done. After couple of these treatments your skin develops a beautiful glow signaling that your body has started recruiting new collagen in the last and. A recommendation of a refresher treatment every 6 months to a year will help you keep your "glow on"!